Meaning The feminine version of Manuel which is a derivative or the name Emmanuel, which means 'God is with us'. Origin of Manuela Spanish +-100%Zoom level changed to 1 Popular Middle Names Aubreyana, Isabella Pronunciation 🔊 Listen Manuela Similar Names Emanuella Emmanuela Ana Isabela Gabrella Marlena Yara Siobhan Elikapeka Marcena Year by Year Popularity of Manuela