Meaning This name is a version of "Jerome," which means holy. Saint Jerome is the patron saint of students and libraries. Origin of Jeronimo Spanish , Greek Popular Middle Names Uriel Pronunciation 🔊 Listen Jeronimo jhe-RON-nih-mow Similar Names Dewey Kasimer Amhuinn Agasthya Lertxun Geron Gnegon Shipley Muqtasid Creketun Year by Year Popularity of Jeronimo