Meaning A girl's name of Irish origin, it means "Melancholy or sorrowful." Origin of Deirdra Irish +-100%Zoom level changed to 1 Popular Middle Names Pronunciation 🔊 Listen Deirdra Similar Names Deidre Deedra Diedre Dedre Tristana Brona Bronagh Burdah Deidra Dores Year by Year Popularity of Deirdra