Meaning A girl's name of German origin, it means "defender of mankind." Origin of Sandra German +-100%Zoom level changed to 1 Popular Middle Names Marie, Renee, Sophia, Victoria, Rose, Rosebella, Mary, May, Noemi, Ann Pronunciation 🔊 Listen Sandra SAN-dra Similar Names Sascha Sacha Saundra Sashenka Sachenka Sachka Alastrina Lexis Raakel Alastriona Year by Year Popularity of Sandra