Meaning A male name of Spanish origin, it means 'God is with us'. Origin of Manolo Spanish +-100%Zoom level changed to 1 Popular Middle Names Brando, David, Diego, Jayson, Jesus, Joaquin, Luis, Lukas, Rivera, Xavier Pronunciation 🔊 Listen Manolo Similar Names Mario Silverio Juanito Godfredo Kiaan Mariano Maka Mariusz Mac Mardonio Year by Year Popularity of Manolo