Meaning This name, which is a female form of "Joseph," means blessed or fertile. Origin of Josefina Spanish , Hebrew Popular Middle Names Christine, Elise, Melinda, Rae, Rose, Tina Pronunciation 🔊 Listen Josefina joe-se-FEE-nuh Similar Names Josephina Benedicta Josepha Josephe Jodi Joseline Josie Jodee Diane Pomona Year by Year Popularity of Josefina