Meaning A boy's name of Hebrew origin, it means "Laughter Variant of Hebrew Isaac." Origin of Itzhak Hebrew +-100%Zoom level changed to 1 Popular Middle Names Pronunciation 🔊 Listen Itzhak Similar Names Izak Isac Izsak Issac Izaac Isacc Yitzchack Izac Ike Itzik Year by Year Popularity of Itzhak