Meaning A girl's name of Arabic origin, it means "Youngest wife of the Prophet (pbuh)." Origin of Ayishah Arabic Popular Middle Names Pronunciation 🔊 Listen Ayishah Similar Names Aaeesha Afsa Fathima Mariam, Maryam Ajwa Ayshah A’ishah Juwariyah Maimoona Safiyyah Year by Year Popularity of Ayishah