Meaning Desti means fate or one's calling. It is more commonly spelled Destiny. Origin of Destini French +-100%Zoom level changed to 1 Popular Middle Names Denise, Faith, Kamryn, Marie Pronunciation 🔊 Listen Destini DES-tih-nee Similar Names Destinee Karma Destine Destinie Destanee Qismah Kismet Qadr Alliana Anaiyah Year by Year Popularity of Destini